Lipoic Acid Chemical Forms: the R and S IsomersWhen Alpha-Lipoic Acid is synthesized in a laboratory, a 50/50 racemicmixture of the R and S enantiomers results in what we call R/S LipoicAcid, which is the most popular form of commercially available LipoicAcid (also named RAS Lipoic Acid or All Racemic Lipoic Acid). Ourpatients know it as simply Alpha Lipoic Acid. New technologicaladvancements have allowed for the stabilization and isolation of theRLA (R-Lipoic Acid isomer), which is believed to account for all thebenefits seen from studies with R/S Lipoic Acid. Supplementing withpure RLA, thus eliminating the presence of SLA (S-Lipoic Acid isomer),creates new opportunities for intensive nutritional support because SLAis believed to interfere with the effectiveness of RLA. How isStabilized R-Lipoic Acid Different From Other R-Lipoic Products on theMarket? R-Lipoic Acid is a highly unstable compound that easilypolymerizes into a sticky rubber or glue-like substance if it is notprepared, stored and processed correctly. This will adversely affectbioavailability. Stable RLA is a non-hygroscopic, non-polymericpotassium salt form of RLA. The capsules are heat stable, characterizedby fast dissolution rates, high solubility and absorption. They arealso free of residual solvents and moisture. There are wide variationsin the R/S ratios and total polymer contents of raw material andfinished products now on the market. Few supplement companies haveexperience with RLA and are unaware of the myriad of problemsassociated with its encapsulation and stability. Designs for Health'sStabilized RLipoic Acid is sourced from the only stable and highlybioavailable form of R-Lipoic Acid available on the market.